First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and time, and pharmacodynamics (PD), the relationship between drug effects and concentration, this handbook examines the relevant relationship between drug effects and time. About the Author: Hartmut Derendorf, Ph.D., is Professor and Chairman of the Department of Pharmaceutics in the College of Pharmacy, University of Florida in Gainesville, Florida.Gunther Hochhaus, Ph.D., is Associate Professor of the Department of Pharmaceutics in the College of Pharmacy, University of Florida in Gainesville, Florida.