This completely updated second edition provides a clear account of how immune responses operate and how parasites can evade immunity. Parasites have evolved to exploit hosts' bodies, whereas hosts have evolved immune systems to control infections. Host-parasite interactions therefore provide fascinating examples of evolutionary "arms-races" in which the immune system plays a key role. Including an expanded section on anti-parasite vaccines, the text focuses on modern research in immunoparasitology directed at understanding and exploiting the capacity to develop effective anti-parasite immunity. The experimental basis of this research is emphasized throughout. The text is aimed at undergraduates and postgraduates with interests in either parasitology or immunology and contains introductory sections on these topics.