This report describes the work performed by the Alaska Exotic Plant Management Team in Wrangell-St. Elias National Park and Preserve during the 2012 season. Three Alaska Exotic Plant Management Team members were stationed at Park Headquarters in Copper Center while working at various locations within the park and preserve. Invasive plant inventories and treatments occurred around the following locations: along the Nabesna road, Kennecott Mines National Historic Landmark, park-owned operations facilities, and several backcountry destinations within park lands. Invasive plant infestations were mapped using Trimble GeoXT units. Manual treatments were performed with the help of volunteers. Data was edited and analyzed using GPS Pathfinder Office and ArcGIS 10. A total of 2,581 pounds of pulled weeds were bagged and then taken to an incinerator in Anchorage to be burned. Gross acres treated increased to 10.8 acres in 2012 from 8 acres in 2011.