This book contains the proceedings of the 2018 International Conference on Bioinformatics and Computational Biology (BIOCOMP'18). Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data. Computational Biology involves the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems. BICOMP is an international conference that serves researchers, scholars, professionals, students, and academicians who are looking to both foster working relationships and gain access to the latest research results.