A new MDO method, BLISS, and two different variants of the method, BLISS/RS and BLISS/S, have been implemented using iSIGHT's scripting language and evaluated in this report on multidisciplinary problems. All of these methods are based on decomposing a modular system optimization system into several subtasks optimization, that may be executed concurrently, and the system optimization that coordinates the subtasks optimization. The BLISS method and its variants are well suited for exploiting the concurrent processing capabilities in a multiprocessor machine. Several steps, including the local sensitivity analysis, local optimization, response surfaces construction and updates are all ideally suited for concurrent processing. Needless to mention, such algorithms that can effectively exploit the concurrent processing capabilities of the compute servers will be a key requirement for solving large-scale industrial design problems, such as the automotive vehicle problem detailed in Section 3.4.Kodiyalam, Srinivas and Yuan, Charles and Sobieski, Jaroslaw (Technical Monitor)Goddard Space Flight Center; Langley Research CenterMULTIDISCIPLINARY DESIGN OPTIMIZATION; CONCURRENT PROCESSING; DESIGN ANALYSIS; SYSTEMS ENGINEERING; PARALLEL PROCESSING (COMPUTERS); MULTIPROCESSING (COMPUTERS); ALGORITHMS; SYSTEMS ANALYSIS...