A rise in the number of young and old patients with stroke has led to the need for better drug development and treatment, as well as diagnosis and prevention for ischemic stroke and mild traumatic brain injury. This book provides a comprehensive overview of advancements in the development of neuroprotective drugs, chemical biomarkers for detection, imaging and preventative strategies. This book will be useful to postgraduate students and researchers in medicinal chemistry and pharmacology as well as specialists in the acute brain injury field.