Section I: Articular Cartilage Lesions: Clinical Management and Regenerative Strategies.- Chapter 1: Knee Articular Cartilage.- Chapter 2: Clinical Management of Articular Cartilage Lesions.- Chapter 3: Synovial Knee Joint Viscosupplementation.- Chapter 4: Ostearthritis Management.- Chapter 5: Advances in Biomaterials for the Repair of Articular Cartilage Defects.- Chapter 6: Cartilage Tissue Engineering and Regenerative Strategies.- Section II: Osteochondral Lesions of the Knee: From Repair towards Regeneration.- Chapter 7: Fundamentals on Osteochondral Tissue Engineering.- Chapter 8: Pre-clinical and Clinical Management of Osteochondral Lesions.- Chapter 9: Rapid Prototyping in Osteochondral Tissue Engineering.- Chapter 10: Biomimetic Approaches for the Engineering of Osteochondral Tissues.- Chapter 11: Osteochondral Tissue Engineering and Regenerative Strategies.- Section III: Meniscus Injuries: Replacement, Repair and Regeneration.- Chapter 12: Basics on Meniscus.- Chapter 13: Biomaterials for Meniscus Repair.- Chapter 14: Advanced Regenerative Strategies.- Section IV: Knee Ligament Injuries.- Chapter 15: Fundamentals on Knee Ligaments and Injuries.- Chapter 16: Clinical Management of Ligament Injuries and Postoperative Rehabilitation.- Chapter 17: Biomaterials as Tendon Substitutes: Current Developments.- Chapter 18: Ligament Tissue Engineering.- Chapter 19: Ligament lesions: Regenerative Strategies and Future Trends.