High Quality Content by WIKIPEDIA articles! Regina ( /rɨˈdʒaɪnə/ "rej-eye-na") is the capital city of the Canadian province of Saskatchewan. The city is the second-largest in the province (after Saskatoon) and a cultural and commercial centre for southern Saskatchewan. It is governed by Regina City Council. Regina is the cathedral city of the Roman Catholic and Romanian OrthodoxDioceses of Regina and the Anglican Diocese of Qu'Appelle. Citizens of Regina are referred to as Reginans. The city is surrounded by the Rural Municipality of Sherwood No. 159.