Rapid industrialization and urbanization fetched both opportunities and challenges to the modern world, amongst which heavy metal pollution remains the most significant challenge. 'Bioremediation' highlights the significance and feasibility of the practical implication of microbes in wastewater treatment. Very limited studies have been demonstrated to understand metal-microbe interaction for most metals. The available studies promise in maintaining environmental sustainability which owes faster and significant attention from researchers to exploit their potential to guarantee the quality of living at all the levels in the ecosystem.