Tooth loss can be effectively and consistently treated with dental implants. The prognosis of a dental implant depends on a plethora of factors. Long-term dental implant failures are still documented, despite the excellent survival rates. These events result in implant removals and further financial and health consequences. While extrinsic variables that increase implant success rates have been well studied, little is known about how hereditary factors affect this issue. This book gives an insight into the genetic factors that might contribute to implant failure and facts to keep in mind while rehabilitating an edentulous patient with dental implants.