The dating world is hard enough as it is. Meet Natasha Murphy: a 30-something serial dater secretly coping with Borderline Personality Disorder. Part 2 of Borderline takes place one year later, amid the pandemic of 2020 and civil unrest in the United States. Not only has the current political climate affect Natasha's mental health, but so has the mandated isolation of shelter-in-place. While briefly abandoning her therapy sessions, Natasha struggles to bridge a relationship with her siblings and mentally ill mother. As if all the chaos in her world isn't enough, Natasha regresses to her old unhealthy habits, including entertaining the wrong men.